3,4-DIHYDRO-2H-PYRAN-6-BORONIC ACID PINACOL ESTER synthesis
- Product Name:3,4-DIHYDRO-2H-PYRAN-6-BORONIC ACID PINACOL ESTER
- CAS Number:1025707-93-0
- Molecular formula:C11H19BO3
- Molecular Weight:210.08
110-87-2
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76-09-5
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$8.19/250mg
121-43-7
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$13.00/25mL
1025707-93-0
58 suppliers
$13.00/100mg
Yield: 50%
Reaction Conditions:
Stage #1:3,4-dihydro-2H-pyran with n-butyllithium;potassium tert-butylate in tetrahydrofuran at -78; for 1 h;Cooling with acetone-dry ice;
Stage #2:Trimethyl borate in tetrahydrofuran at 0; for 1 h;Cooling with ice;
Stage #3:2,3-dimethyl-2,3-butane diol in tetrahydrofuran;acetic acid at 20;
References:
Butkevich, Alexey N.;Corbu, Andrei;Cossy, Janine;Meerpoel, Lieven;Bonnet, Pascal;Stansfield, Ian;Angibaud, Patrick [Organic Letters,2012,vol. 14,# 19,p. 4998 - 5001,4] Location in patent:supporting information
110-87-2
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$10.00/1g
73183-34-3
581 suppliers
$6.00/5g
1046811-99-7
50 suppliers
$97.00/100mg
1025707-93-0
58 suppliers
$13.00/100mg
110-87-2
525 suppliers
$10.00/1g
25015-63-8
222 suppliers
$22.39/5G
1046811-99-7
50 suppliers
$97.00/100mg
1025707-93-0
58 suppliers
$13.00/100mg