3-(4'-METHOXYPHENYL)PROPYL CHLORIDE synthesis

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: O₃ / CH₂Cl₂; methanol / -78 °C
1.2: 73 percent / Ph₃P / CH₂Cl₂; methanol / 0.5 h
2.1: 76 percent / CH₂Cl₂ / 5 h / Heating
3.1: H₂ / 10 percent Pd/C / ethyl acetate / 20 °C
3.2: 76 percent / LiAlH₄ / tetrahydrofuran / 5 h / Heating
4.1: 78 percent / CCl₄; Ph₃P / 8 h / Heating

References:

Fronza, Giovanni;Fuganti, Claudio;Serra, Stefano;Cisero, Marco;Koziet, Joseph [Journal of agricultural and food chemistry,2002,vol. 50,# 10,p. 2748 - 2754]