3-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazole synthesis
1synthesis methods
- Product Name:3-[(4-nitrobenzyl)sulfanyl]-4H-1,2,4-triazole
- CAS Number:296272-93-0
- Molecular formula:C9H8N4O2S
- Molecular Weight:236.25
Yield:296272-93-0 83%
Reaction Conditions:
Stage #1: 3-mercapto-1,2,4-triazolewith sodium in methanol;1,2-dimethoxyethane at 20; for 0.166667 h;
Stage #2: 4-nitrobenzyl chloride in methanol;1,2-dimethoxyethane at 20; for 23 h;
References:
Klimesova, Vera;Zahajska, Lenka;Waisser, Karel;Kaustova, Jarmila;Moellmann, Ute [Il Farmaco,2004,vol. 59,# 4,p. 279 - 288]