3-(4-NITROPHENOXY)BENZOIC ACID synthesis
- Product Name:3-(4-NITROPHENOXY)BENZOIC ACID
- CAS Number:27237-21-4
- Molecular formula:C13H9NO5
- Molecular Weight:259.21
99-06-9
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350-46-9
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27237-21-4
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Yield:27237-21-4 98%
Reaction Conditions:
with potassium carbonate in dimethyl sulfoxide at 130; for 12 h;
Steps:
1
Synthesis Example 1 3-(4-nitrophenoxy)benzoic acid 7.52 ml of fluoro-4-nitrobenzene (70.8 mmol) and 9.79 g of 3-hydroxybenzoic acid (70.8 mmol) were dissolved in 150 ml of DMSO at room temperature, 21 g of potassium carbonate (151.9 mmol) was added thereto, heated to 130° C. and then reacted for 12 hours. The reactant solution was poured into excess water, neutralized with hydrochloric acid, filtered, and dried to yield a product having Formula 25 as a white powder (18.7 g, Yield 98%). 1H NMR (300 MHz, CDCl3) analytical results of the product were as follows: 1H NMR (300 MHz, CDCl3): [ppm] 7.03 (d, 2H), 7.33 (d, 1H), 7.54 (t, 1H), 7.80 (s, 1H), 7.98 (d, 1H), 8.22 (d, 2H), 12.70 (s, 1H)
References:
US2012/46472,2012,A1 Location in patent:Page/Page column 9
284462-55-1
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27237-21-4
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99-06-9
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$5.00/25g
100-00-5
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27237-21-4
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2303-25-5
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27237-21-4
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100-00-5
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27237-21-4
40 suppliers
$137.84/250mgs: