3,5-Bis(trifluoromethyl)nitrobenzene synthesis
- Product Name:3,5-Bis(trifluoromethyl)nitrobenzene
- CAS Number:328-75-6
- Molecular formula:C8H3F6NO2
- Molecular Weight:259.11
402-31-3
341 suppliers
$6.00/25g
328-75-6
165 suppliers
$12.00/5g
Yield: 95%
Reaction Conditions:
with sulfuric acid;nitric acid at 35; for 1 h;
Steps:
1-3 Preparation of 3,5-bistrifluoromethylnitrobenzene
Put 214g (1mol) m-bistrifluoromethylbenzene and 300g (3mol) 98% sulfuric acid into a 1L four-necked flask, and then add 98g (1.5mol) 97% nitric acid and 300g (3mol) 98% sulfuric acid dropwise at about 35 The prepared mixed acid was dripped and kept for 1 hour, then left to stand for layering, the oil layer was washed with water, alkali washed, and then washed with water to obtain 3,5-bistrifluoromethylnitrobenzene with a purity of 99% and a yield of 95%.
References:
Zhejiang Yongtai Technology Co., Ltd.;Shao Hongming;Li Fei;Chen Shaoting;Li Hongkui;Sun Zhen CN111960917, 2020, A Location in patent:Paragraph 0053-0061
618-88-2
480 suppliers
$13.00/25g
328-75-6
165 suppliers
$12.00/5g
