![](/CAS/GIF/1956-30-5.gif)
3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE synthesis
- Product Name:3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE
- CAS Number:1956-30-5
- Molecular formula:C13H15IN2O7
- Molecular Weight:438.17
![Idoxuridine](/CAS/GIF/54-42-2.gif)
54-42-2
438 suppliers
$6.00/250mg
![3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE](/CAS/GIF/1956-30-5.gif)
1956-30-5
37 suppliers
$130.00/100mg
Yield:-
Reaction Conditions:
with HClO4;acetic anhydride in acetic acid;
Steps:
2 3',5'-Di-O-Acetyl-5-iodo-2'-deoxyuridine (2.2)
3',5'-Di-O-Acetyl-5-iodo-2'-deoxyuridine (2.2) To 5-iodo-2'-deoxyuridine (2.1) (70.8 g, 200 mmol, 1 eq) in an 500 mL Erlenmeyer flask was added acetic acid (72 g, 68.7 mL, 1200 mmol, 6 eq) and acetic anhydride (51 g, 47.1 mL, 500 mmol, 2.5 eq). In a test tube at 0° C., the catalyst for the reaction was prepared by adding HClO4 (0.5 mL) over acetic anhydride (2 mL). Five drops of the catalyst were added into the Erlenmeyer flask at 0° C. with stirring. The reaction mixture was brought to room temperature and stirred for 4 hours where upon a thick white precipitate formed.
References:
US6444682,2002,B1
![3,5'-Di-O-acetyl-2'-deoxyuridine](/CAS/GIF/13030-62-1.gif)
13030-62-1
37 suppliers
$125.00/250mg
![3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE](/CAS/GIF/1956-30-5.gif)
1956-30-5
37 suppliers
$130.00/100mg
![Idoxuridine](/CAS/GIF/54-42-2.gif)
54-42-2
438 suppliers
$6.00/250mg
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE](/CAS/GIF/1956-30-5.gif)
1956-30-5
37 suppliers
$130.00/100mg
![2'-Deoxyuridine](/CAS/GIF/951-78-0.gif)
951-78-0
475 suppliers
$5.00/100mg
![3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE](/CAS/GIF/1956-30-5.gif)
1956-30-5
37 suppliers
$130.00/100mg
![Idoxuridine](/CAS/GIF/54-42-2.gif)
54-42-2
438 suppliers
$6.00/250mg
![Acetyl chloride](/CAS/GIF/75-36-5.gif)
75-36-5
561 suppliers
$17.92/100G
![3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE](/CAS/GIF/1956-30-5.gif)
1956-30-5
37 suppliers
$130.00/100mg