ChemicalBook CAS DataBase List 3,5-Dichlorobenzoyl chloride

3,5-Dichlorobenzoyl chloride synthesis

11synthesis methods

Product Name:3,5-Dichlorobenzoyl chloride
CAS Number:2905-62-6
Molecular formula:C7H3Cl3O
Molecular Weight:209.46

3,5-Dichlorobenzoyl chloride is obtained by reacting by aryl carboxylic acid with DMF.Dissolve aryl carboxylic acid (10.0 mmol) in 50 mL DCM with drops of DMF to a 100 mL roundbottomed flask. Cool the mixture to 0°C. Add oxalyl chloride (20.0 mmol, 2.0 equivalents) dropwise to the reaction mixture. Allow the reaction mixture to react for another 4 hours. Concentrate the solvent in vacuo. Use the remaining residue directly.

Fig The synthetic method of 3,5-Dichlorobenzoyl chloride

51-36-5 Synthesis

51-36-5
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2905-62-6
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$13.43/1gm:

Yield:2905-62-6 100%

Reaction Conditions:

with thionyl chloride for 5 h;Reflux;

Steps:

12.1 3,5-dichlorobenzoyl chloride

3,5-Dichlorobenzoic acid 2a (5.0 g, 26.2 mmol) was dissolved in 50 mL of thionyl chloride and refluxed for 5 hours. Concentration under reduced pressure and removal of thionyl chloride afforded crude 3,5-dichlorobenzoyl chloride 12a (5.5 g, yellow oil). Yield: 100%.

References:

CN109574927,2019,A Location in patent:Paragraph 0439; 0441-0444

65-85-0 Synthesis