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ChemicalBook CAS DataBase List 3’,5’-Difluoro-2-hydroxyacetophenone
1260403-62-0

3’,5’-Difluoro-2-hydroxyacetophenone synthesis

3synthesis methods
Ethanone, 2-(acetyloxy)-1-(3,5-difluorophenyl)-

1260403-63-1
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3’,5’-Difluoro-2-hydroxyacetophenone

1260403-62-0
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Yield:1260403-62-0 86%

Reaction Conditions:

with hydrogenchloride;water in methanol at 40;Inert atmosphere;

References:

McLaughlin, Mark;Belyk, Kevin M.;Qian, Gang;Reamer, Robert A.;Chen, Cheng-Yi [Journal of Organic Chemistry,2012,vol. 77,# 11,p. 5144 - 5148] Location in patent:experimental part