![](/CAS/GIF/132980-99-5.gif)
3,5-DIFLUOROBENZAMIDE synthesis
- Product Name:3,5-DIFLUOROBENZAMIDE
- CAS Number:132980-99-5
- Molecular formula:C7H5F2NO
- Molecular Weight:157.12
![3,5-Difluorobenzonitrile](/CAS/GIF/64248-63-1.gif)
64248-63-1
297 suppliers
$6.00/5g
![3,5-DIFLUOROBENZAMIDE](/CAS/GIF/132980-99-5.gif)
132980-99-5
96 suppliers
$19.00/5g
Yield: 100%
Reaction Conditions:
with [{Au(IPr)}2(μ-OH)][BF4];water in tetrahydrofuran at 140; under 5250.53 Torr; for 2 h;Sealed tube;Microwave irradiation;Reagent/catalyst;
Steps:
A Hydration of Nitriles
In a typical reaction, [Au(IPr)(NTf2)] (13 mg, 20 μmol, 2 mol %) or [{Au(IPr)}2(μ-OH)]BF4 (17 mg, 10 μmol, 1 mol %) was added to THF (0.5 mL) in a 2 mL microwave vial in air. Benzonitrile (103 mg, 1 mmol) was added, followed by distilled H2O (500 μL). The vial was sealed and heated in the microwave for 2 h at 140° C. (7 bar). The conversion was determined by gas chromatography
References:
University Court of The University of St. Andrews;Nolan, Steven P. US2013/35322, 2013, A1 Location in patent:Paragraph 0112
![3,5-Difluorobenzaldehyde](/CAS/GIF/32085-88-4.gif)
32085-88-4
263 suppliers
$19.00/25g
![3,5-DIFLUOROBENZAMIDE](/CAS/GIF/132980-99-5.gif)
132980-99-5
96 suppliers
$19.00/5g
![3,5-Difluorobenzoyl chloride](/CAS/GIF/129714-97-2.gif)
129714-97-2
144 suppliers
$14.00/1g
![3,5-DIFLUOROBENZAMIDE](/CAS/GIF/132980-99-5.gif)
132980-99-5
96 suppliers
$19.00/5g
![3,5-Difluorobenzoic acid](/CAS/GIF/455-40-3.gif)
455-40-3
305 suppliers
$10.00/5g
![3,5-DIFLUOROBENZAMIDE](/CAS/GIF/132980-99-5.gif)
132980-99-5
96 suppliers
$19.00/5g