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ChemicalBook CAS DataBase List 3,5-DIIODOTHYROACETIC ACID

3,5-DIIODOTHYROACETIC ACID synthesis

13synthesis methods
-

Yield: 95%

Reaction Conditions:

with phosphorus;hydrogen iodide;acetic acid for 1 h;Reflux;

Steps:


[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid (8)The title compound was prepared as described by Wilkinson J H Synthesis of some Possible Metabolites of Thyroxin and Triiodothyronine Biochem J. 1956 August; 63(4):601-605.

References:

VASCULAR VISION PHARMACEUTICAL COMPANY US2011/105482, 2011, A1 Location in patent:Page/Page column 10

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