3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL& synthesis
- Product Name:3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&
- CAS Number:60319-09-7
- Molecular formula:C9H9F3O5S
- Molecular Weight:286.23
500-99-2
264 suppliers
$10.00/1g
421-83-0
234 suppliers
$22.39/1G
60319-09-7
14 suppliers
$112.00/5g
Yield:60319-09-7 90%
Reaction Conditions:
with sodium carbonate in toluene at 5 - 20; for 8 h;
Steps:
1.1
(1), 3,5-dimethoxyphenol (0.8mol, 123.3g), Sodium carbonate (0.8mol, 84.8g),Toluene (500mL) was added to a 1L four-necked flask,Stir well,Cool down to 5,Start slowly adding trifluoromethanesulfonyl chloride (0.8mol, 134.8g) dropwise,After the addition, the temperature was raised to 20°C and the reaction was stirred for 8h.After the reaction, it was cooled, washed with water until the organic phase was neutral, the water phase was separated, and the organic phase was distilled under reduced pressure to recover the solvent to obtain a colorless liquid as 3,5-dimethoxyphenyl trifluoromethanesulfonate (205.9 g), the yield is 90%;
References:
CN111393265,2020,A Location in patent:Paragraph 0039-0041
500-99-2
264 suppliers
$10.00/1g
358-23-6
585 suppliers
$10.00/1g
60319-09-7
14 suppliers
$112.00/5g