3,5-DIPHENYL-4,5-DIHYDRO-1H-PYRAZOLE synthesis

9synthesis methods

Product Name:3,5-DIPHENYL-4,5-DIHYDRO-1H-PYRAZOLE
CAS Number:16619-60-6
Molecular formula:C15H14N2
Molecular Weight:222.29

614-47-1 Synthesis

614-47-1
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1145-01-3 Synthesis

1145-01-3
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$10.00/1g

16619-60-6
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Yield:1145-01-3 97.8%

Reaction Conditions:

with hydrazine hydrate in methanol;

Steps:

9 EXAMPLE 9

EXAMPLE 9 There are reacted 12.5 parts of benzalacetophenone and 3.1 parts (by volume) of hydrazine hydrate in methanol to form 3,5-diphenyl-2-pyrazoline. To the latter is added then 5% palladium on carbon catalyst (2 parts) and the reaction mixture is heated at reflux for 1 hour and 20 minutes. The product, 3,5-diphenylpyrazole, is obtained in 97.8% yield.

References:

US3952010,1976,A US4014896,1977,A

94-41-7 Synthesis