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3-(5-Oxazolyl)benzaldehyde synthesis

1synthesis methods
3132-99-8 Synthesis
3-Bromobenzaldehyde

3132-99-8
478 suppliers
$5.00/10g

2-Triisopropylsilyl-oxazole-5-boronic acid, pinacol ester

1186127-11-6
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3-(5-Oxazolyl)benzaldehyde

1097199-51-3
27 suppliers
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Yield:1097199-51-3 67%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium(0);water;sodium carbonate in 1,4-dioxane at 80;Inert atmosphere;Suzuki cross-coupling;

References:

Primas, Nicolas;Bouillon, Alexandre;Lancelot, Jean-Charles;Rault, Sylvain [Tetrahedron,2009,vol. 65,# 32,p. 6348 - 6353] Location in patent:experimental part