ChemicalBook CAS DataBase List 3,6-dibromo-4,5-difluoro-1,2-phenylenediamine

3,6-dibromo-4,5-difluoro-1,2-phenylenediamine synthesis

9synthesis methods

Product Name:3,6-dibromo-4,5-difluoro-1,2-phenylenediamine
CAS Number:1345627-73-7
Molecular formula:C6H4Br2F2N2
Molecular Weight:301.91

1,4-dibroMo-2,3-difluoro-5,6-dinitrobenzene

1283598-32-2
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3,6-dibromo-4,5-difluoro-1,2-phenylenediamine

1345627-73-7
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Yield:1345627-73-7 89%

Reaction Conditions:

with iron;acetic acid at 45; for 6 h;Inert atmosphere;

Steps:

4 2.2.4 3,6-Dibromo-4,5-difluorobenzene-1,2-diamine (4)

In a 250mL two-neck round-bottom flask, 1,4-dibromo-2,3-difluoro-5,6-dinitrobenzene 3 (3.3g, 9.2mmol), iron powder (7.3g, 130mmol) and acetic acid (130mL) were stirred at 45°C for 6h under argon protection. The solution was cooled down to room temperature and poured into cold 5% NaOH solution (400mL). Then ethyl acetate was added to extract the organic part three times. The ethyl acetate phase was washed with NaHCO₃ solution, dried with anhydrous MgSO₄, and then the solvent was removed under vacuum to yield 2.5g (89%) of the product as light yellow powder. ¹H NMR (300MHz, DMSO) δ (ppm): 5.16 (s, 4H). ¹³C NMR (75MHz, DMSO) δ (ppm): 141.07, 140.83, 137.97, 130.06, 130.04, 94.65, 94.50, 94.36.

References:

Liu, Xuncheng;Cai, Ping;Chen, Zhenhui;Zhang, Lianjie;Zhang, Xiaofei;Sun, Jiangman;Wang, Haitao;Chen, Junwu;Peng, Junbiao;Chen, Hongzheng;Cao, Yong [Polymer,2014,vol. 55,# 7,p. 1707 - 1715]

4,7-dibroMo-5,6-difluorobenzo[c][1,2,5]thiadiazole

1295502-53-2
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1345627-73-7
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References

867366-94-7 Synthesis

(2,3-difluoro-1,4-phenylene)bis(triMethylsilane)

867366-94-7
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$956.12/5g

1345627-73-7
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References

367-11-3
306 suppliers
$10.00/1g

1345627-73-7
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References

156682-52-9 Synthesis

156682-52-9
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$9.00/1g

1345627-73-7
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References