ChemicalBook CAS DataBase List 3-ALLYL-4-HYDROXY-5-METHOXY-BENZALDEHYDE

3-ALLYL-4-HYDROXY-5-METHOXY-BENZALDEHYDE synthesis

5synthesis methods

Product Name:3-ALLYL-4-HYDROXY-5-METHOXY-BENZALDEHYDE
CAS Number:20240-58-8
Molecular formula:C11H12O3
Molecular Weight:192.21

22280-95-1
18 suppliers
$63.00/500mg

3-ALLYL-4-HYDROXY-5-METHOXY-BENZALDEHYDE

20240-58-8
19 suppliers
$46.00/1g

Yield:20240-58-8 92%

Reaction Conditions:

in 1-methyl-pyrrolidin-2-one at 200; for 3 h;Microwave irradiation;

Steps:

5 Example 5:Synthesis of 3-allyl-4-hydroxy-5-methoxybenzaldehyde (d):

After 5 g (26 mmol) of 4-allyloxy-3-methoxybenzaldehyde (c) was weighed and dissolved in 20 ml of NMP (N-methylpyrrolidone), microwave reaction was performed at 200 ° C for 3 hours.Add appropriate amount of water to the system to dilute and extract with dichloromethane. After combining the organic phases,Wash with saturated NaCl solution, dry with anhydrous sodium sulfate, spin dry the system,A crude product was obtained.The crude product was separated and purified by column chromatography (eluent: petroleum ether-ethyl acetate).4.6 g of white solid was obtained,The yield was 92%.

References:

CN110229056,2019,A Location in patent:Paragraph 0104-0106

121-33-5 Synthesis