![](/CAS/GIF/14966-91-7.gif)
3-AMINO-6-PHENYLPYRIDAZINE synthesis
- Product Name:3-AMINO-6-PHENYLPYRIDAZINE
- CAS Number:14966-91-7
- Molecular formula:C10H9N3
- Molecular Weight:171.2
![6-Chloropyridazin-3-amine](/CAS/GIF/5469-69-2.gif)
5469-69-2
368 suppliers
$6.00/10g
![Phenylboronic acid](/CAS/GIF/98-80-6.gif)
98-80-6
717 suppliers
$5.00/5g
![3-AMINO-6-PHENYLPYRIDAZINE](/CAS/GIF/14966-91-7.gif)
14966-91-7
63 suppliers
$52.00/100 mg
Yield: 79%
Reaction Conditions:
with tetrakis(triphenylphosphine) palladium(0);potassium carbonate in 1,4-dioxane;water;toluene for 12 h;Reflux;
Steps:
11-3; 6
General procedure: phenylboronic acid (8.9 g, 0.073 mol), 4-bromo-2-naphthylamine (13.5 g, 0.061 mol), tetrakis(triphenylphosphine)palladium (3.62 g, 0.003 mol), potassium carbonate (25.3) g, 0.183 mol) was added to 75 mL of 1,4-dioxane, 75 mL of toluene, and 30 mL of distilled water, and refluxed for 12 hours.After cooling to room temperature, extraction with ethyl acetate, and separation by column chromatography to give [Intermediate 1-c] 10 g (75% yield).
References:
SFC Ltd.;Cha Sun-uk;Jeong Gyeong-seok;Park Seok-bae;Kim Hui-dae;Lee Yu-rim;Song Ju-man;Hwang Mun-chan KR102193832, 2020, B1 Location in patent:Paragraph 0198; 0207-0210; 0320-0324
![6-BROMO-3-PYRIDAZINAMINE](/CAS/GIF/88497-27-2.gif)
88497-27-2
147 suppliers
$41.71/1gm:
![Phenylboronic acid](/CAS/GIF/98-80-6.gif)
98-80-6
717 suppliers
$5.00/5g
![3-AMINO-6-PHENYLPYRIDAZINE](/CAS/GIF/14966-91-7.gif)
14966-91-7
63 suppliers
$52.00/100 mg
![3-hydrazino-6-phenylpyridazine](/CAS/GIF/38956-80-8.gif)
38956-80-8
32 suppliers
$35.00/200 μmol
![3-AMINO-6-PHENYLPYRIDAZINE](/CAS/GIF/14966-91-7.gif)
14966-91-7
63 suppliers
$52.00/100 mg
![3-CHLORO-6-PHENYLPYRIDAZINE](/CAS/GIF/20375-65-9.gif)
20375-65-9
136 suppliers
$15.00/250mg
![3-AMINO-6-PHENYLPYRIDAZINE](/CAS/GIF/14966-91-7.gif)
14966-91-7
63 suppliers
$52.00/100 mg
![6-iodopyridazin-3-amine](/CAS2/GIF/187973-60-0.gif)
187973-60-0
95 suppliers
$9.00/100mg
![Phenylboronic acid](/CAS/GIF/98-80-6.gif)
98-80-6
717 suppliers
$5.00/5g
![3-AMINO-6-PHENYLPYRIDAZINE](/CAS/GIF/14966-91-7.gif)
14966-91-7
63 suppliers
$52.00/100 mg