ChemicalBook CAS DataBase List 3-(BENZYLOXY)-2-METHYL-4H-PYRAN-4-ONE

3-(BENZYLOXY)-2-METHYL-4H-PYRAN-4-ONE synthesis

6synthesis methods

Product Name:3-(BENZYLOXY)-2-METHYL-4H-PYRAN-4-ONE
CAS Number:61049-69-2
Molecular formula:C13H12O3
Molecular Weight:216.23

118-71-8 Synthesis

118-71-8
602 suppliers
$5.00/25mg

100-44-7 Synthesis

100-44-7
630 suppliers
$13.50/250G

61049-69-2
86 suppliers
$68.00/25 mg

Yield: 99.4%

Reaction Conditions:

with potassium carbonate in acetonitrile for 5 h;Reflux;

Steps:

4.1 Example 1 Preparation of 3-benzyloxy-2-methyl-4H-pyran-4-one
10.0 g of 3-hydroxy-2-methyl-4H-pyran-4-one and 16.4 g of potassium carbonate were added to 300 ml of acetonitrile.12.0 g of benzyl chloride was added, and the mixture was heated to reflux. After 5 hours, TLC ( petroleum ether: ethyl acetate = 1:1) was obtained.The reaction solution was cooled to room temperature, suction filtered, and the filter cake was washed with 100 ml of ethyl acetate, and the filtrate was directly dried.3-benzyloxy-2-methyl-4H-pyran-4-one 17.0 g was obtained in a yield: 99.4%.

References:

Shandong Bainuo Pharmaceutical Co., Ltd.;Chen Jingjin;Zhao Xiandong;Gao Chao;Zhen Yizhan CN109912553, 2019, A Location in patent:Paragraph 0067-0070

118-71-8 Synthesis

118-71-8
602 suppliers
$5.00/25mg