![](/CAS/GIF/59214-70-9.gif)
3-BROMO-1-BENZOFURAN synthesis
- Product Name:3-BROMO-1-BENZOFURAN
- CAS Number:59214-70-9
- Molecular formula:C8H5BrO
- Molecular Weight:197.03
![2,3-dibromo-2,3-dihydro-benzo[b]furan](/CAS/20180703/GIF/109210-15-3.gif)
109210-15-3
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![3-BROMO-1-BENZOFURAN](/CAS/GIF/59214-70-9.gif)
59214-70-9
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$11.00/250mg
Yield:59214-70-9 90%
Reaction Conditions:
with potassium hydroxide in ethanol at 0; for 2 h;Heating / reflux;
Steps:
9.22
Potassium hydroxide pellets (9.3 g, 165 mmol) are dissolved in ethanol (40 mL) and cooled to 0° C. 2,3-Dibromo-2,3-dihydro-benzo[b]furan (23.0 g, 82.7 mmol) dissolved in ethanol (90 mL) is added dropwise hereto at a constant temperature of 0° C. After complete addition the mixture is heated to reflux for 2 hours. The mixture is concentrated in vacuo and water (100 mL) is added. The aqueous layer is extracted with ethyl acetate (3×100 mL). The combined organic fractions are washed with brine (100 mL), dried (MgSO4) and concentrated to furnish 14.7g (90%) of the wanted product as an oil.
References:
US2006/287386,2006,A1 Location in patent:Page/Page column 17
![Benzofuran](/CAS/GIF/271-89-6.gif)
271-89-6
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$9.00/1g
![3-BROMO-1-BENZOFURAN](/CAS/GIF/59214-70-9.gif)
59214-70-9
148 suppliers
$11.00/250mg
![2,3-Dibromobenzofuran](/CAS/20150408/GIF/64150-61-4.gif)
64150-61-4
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![Benzofuran](/CAS/GIF/271-89-6.gif)
271-89-6
250 suppliers
$9.00/1g
![3-BROMO-1-BENZOFURAN](/CAS/GIF/59214-70-9.gif)
59214-70-9
148 suppliers
$11.00/250mg
![2,3-Dibromobenzofuran](/CAS/20150408/GIF/64150-61-4.gif)
64150-61-4
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![3-BROMO-1-BENZOFURAN](/CAS/GIF/59214-70-9.gif)
59214-70-9
148 suppliers
$11.00/250mg
![Benzofuran, 2,3-dibromo-2,3-dihydro-, (2R,3S)-rel-](/CAS/20210305/GIF/58863-52-8.gif)
58863-52-8
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![3-BROMO-1-BENZOFURAN](/CAS/GIF/59214-70-9.gif)
59214-70-9
148 suppliers
$11.00/250mg