3-Bromo-1-benzothiophen-2-amine synthesis

7synthesis methods

Product Name:3-Bromo-1-benzothiophen-2-amine
CAS Number:344747-99-5
Molecular formula:C8H6BrNS
Molecular Weight:228.11

17402-78-7 Synthesis

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Yield: 99%

Reaction Conditions:

with iron;acetic acid in ethanol at 60; for 1 h;

Steps:

15 Preparation of Compound 8-2
Compound 8-1 9g (34.87mmol) was stirred with 300mL of ethanol, put into an iron powder (Fe Powder) 6.03g (108.1mmol) for 10 minutes at room temperature respectively. 30mL acetic acid was added dropwise thereto slowly and the mixture was refluxed for 1 hour at 60°C. After completion of the reaction after cooling to room temperature, H2O After filtration, the solid that was generated by the addition of H2O and washed with hexane to give 7.9g of the desired compound 8-2 (99%).

References:

Heesung Material Co., Ltd;Lee, Jong Hyon;Noh, Young-seok;Park, Gon Yu;Kim, Dong-jun;Kim, Gi Young;Choe, Jin Seok;Choe, Dai Hyok;Um, Song Jean;Lee, Joo Dong KR2016/1702, 2016, A Location in patent:Paragraph 0267-0268; 0271-0272

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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References

39827-11-7 Synthesis

39827-11-7
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$17.00/1g

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References

1000210-73-0
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89673-36-9 Synthesis

tert-butyl benzo[b]thiophen-2-ylcarbaMate

89673-36-9
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$11.00/100mg

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References