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3-broMo-5-(3,4-dihydro-2H-pyrrol-5-yl)pyridine synthesis

4synthesis methods
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Yield:64319-85-3 72%

Reaction Conditions:

Stage #1: 1-ethenyl-2-pyrrolidinone;ethyl 5-bromo-3-pyridinecarboxylatewith sodium hydride in tetrahydrofuran; for 1 h;Heating;
Stage #2: with hydrogenchlorideHeating;Further stages.;

References:

Isomura;Wirsching;Janda [Journal of Organic Chemistry,2001,vol. 66,# 12,p. 4115 - 4121]