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823222-22-6

3-bromo-5-chloro-2-(trifluoromethyl)pyridine synthesis

3synthesis methods
81290-20-2 Synthesis
(Trifluoromethyl)trimethylsilane

81290-20-2
408 suppliers
$13.00/1g

823221-97-2 Synthesis
3-bromo-5-chloro-2-iodopyridine

823221-97-2
49 suppliers
$21.00/100mg

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Yield:823222-22-6 69%

Reaction Conditions:

with 1-methyl-pyrrolidin-2-one;potassium fluoride;copper(l) iodideHeating;

References:

Cottet, Fabrice;Schlosser, Manfred [Tetrahedron,2004,vol. 60,# 51,p. 11869 - 11874]