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3-Chloro-2,2-dimethylpropionic acid methyl ester synthesis

7synthesis methods
-

Yield:21491-96-3 92.7%

Steps:

2 EXAMPLE 2

After the evolution of SO2 had ended, isolation by distillation gave 524.8 g (3.48 mol) of methyl 2,2-dimethyl-3-chloropropionate (boiling point 82° C./5 mbar), corresponding to a 92.7% yield, based on methyl hydroxypivalate.

References:

US4837357,1989,A