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ChemicalBook CAS DataBase List 3-chloro-2-hydroxybenzonitrile

3-chloro-2-hydroxybenzonitrile synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine; magnesium chloride / tetrahydrofuran / 8 h / 80 °C
2: ammonium hydroxide; iodine / tetrahydrofuran / 2 h / 0 - 20 °C

References:

Nakai, Yuhta;Moriyama, Katsuhiko;Togo, Hideo [European Journal of Organic Chemistry,2014,vol. 2014,# 27,p. 6077 - 6083]

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