3-CHLORO-L-TYROSINE synthesis
1synthesis methods
- Product Name:3-CHLORO-L-TYROSINE
- CAS Number:70680-93-2
- Molecular formula:C9H10ClNO3
- Molecular Weight:215.63
Yield: 50%
Reaction Conditions:
with recombinant tyrosine phenol lyase M379V from Citrobacter freundii;ammonium chloride in aq. phosphate buffer at 21; for 24 h;Enzymatic reaction;regioselective reaction;
References:
Busto, Eduardo;Simon, Robert C.;Kroutil, Wolfgang [Angewandte Chemie - International Edition,2015,vol. 54,# 37,p. 10899 - 10902][Angew. Chem.,2015,vol. 127,p. 11049 - 11052,4] Location in patent:supporting information