ChemicalBook CAS DataBase List 3-(CHLOROMETHYL)-5-(3,4-DICHLOROPHENYL)ISOXAZOLE

3-(CHLOROMETHYL)-5-(3,4-DICHLOROPHENYL)ISOXAZOLE synthesis

3synthesis methods

Product Name:3-(CHLOROMETHYL)-5-(3,4-DICHLOROPHENYL)ISOXAZOLE
CAS Number:338776-97-9
Molecular formula:C10H6Cl3NO
Molecular Weight:262.52

6287-38-3 Synthesis

6287-38-3
254 suppliers
$8.00/10g

3-(CHLOROMETHYL)-5-(3,4-DICHLOROPHENYL)ISOXAZOLE

338776-97-9
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Yield:-

Steps:

Multi-step reaction with 6 steps
1: tetrahydrofuran / 3.17 h / 0 - 20 °C / Inert atmosphere
2: silica gel; manganese(IV) oxide / acetonitrile / 8 h / 70 °C / Molecular sieve
3: sodium hydride / toluene / 2 h / 90 °C
4: hydroxylamine hydrochloride / ethanol / 2 h / Reflux
5: sodium tetrahydroborate / ethanol; water / 20 °C
6: 1,2,3-Benzotriazole; thionyl chloride / dichloromethane / 20 °C

References:

Bi, Fangchao;Song, Di;Zhang, Nan;Liu, Zhiyang;Gu, Xinjie;Hu, Chaoyu;Cai, Xiaokang;Venter, Henrietta;Ma, Shutao [European Journal of Medicinal Chemistry,2018,vol. 159,p. 90 - 103]

2642-63-9 Synthesis

2642-63-9
189 suppliers
$6.00/5g

338776-97-9
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References

1475-11-2
48 suppliers
$26.00/1g

338776-97-9
6 suppliers
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References