3-cyclopropoxyaniline synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1: caesium carbonate / N,N-dimethyl-formamide / 32 h / 130 °C
2: hydrogen; palladium on activated charcoal / methanol / 2 h / 25 °C / 775.74 Torr

References:

MERCK SHARP & DOHME CORP.;CALDWELL, John, P.;CAPLEN, Mary Ann;CUMMING, Jared, N.;DYKSTRA, Kevin, D.;HRUZA, Alan;LANKIN, Claire;LI, Derun;LIU, Hong;MCCRACKEN, Amy;MCKITTRICK, Brian;RAO, Ashwin;TAGAT, Jayaram, R.;TANG, Haiqun;TAOKA, Brandon, M.;VERRAS, Andreas;WALSH, Shawn, P.;WU, Wen-Lian;ZHANG, Tianyuan WO2018/34917, 2018, A1