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3-(Dimethylcarbamoyl)Benzoic Acid synthesis

2synthesis methods
-

Yield:858981-15-4 100%

Reaction Conditions:

with water;lithium hydroxide in tetrahydrofuran;methanol at 20; for 21 h;

References:

Keurulainen, Leena;Vahermo, Mikko;Puente-Felipe, Margarita;Sandoval-Izquierdo, Elena;Crespo-Fernández, Benigno;Guijarro-López, Laura;Huertas-Valentín, Leticia;De Las Heras-Due?a, Laura;Leino, Teppo O.;Siiskonen, Antti;Ballell-Pages, Lluís;Sanz, Laura M.;Casta?eda-Casado, Pablo;Jiménez-Díaz, M. Belén;Martínez-Martínez, María S.;Viera, Sara;Kiuru, Paula;Calderón, Félix;Yli-Kauhaluoma, Jari [Journal of Medicinal Chemistry,2015,vol. 58,# 11,p. 4573 - 4580] Location in patent:supporting information