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3-(ethoxycarbonyl)-1,2-oxazole-5-carboxylic acid synthesis

3synthesis methods
123770-62-7 Synthesis
ETHYL 5-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLATE

123770-62-7
69 suppliers
$39.00/100mg

3-(ethoxycarbonyl)-1,2-oxazole-5-carboxylic acid

133674-44-9
6 suppliers
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Yield:133674-44-9 88%

Reaction Conditions:

with Jones reagent in acetone at 55; for 2 h;

References:

Mao, Jialin;Yuan, Hai;Wang, Yuehong;Wan, Baojie;Pieroni, Marco;Huang, Qingqing;Van Breemen, Richard B.;Kozikowski, Alan P.;Franzblau, Scott G. [Journal of Medicinal Chemistry,2009,vol. 52,# 22,p. 6966 - 6978] Location in patent:experimental part