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ChemicalBook CAS DataBase List 3-Ethyl-4-(hydroxyMethyl)benzonitrile

3-Ethyl-4-(hydroxyMethyl)benzonitrile synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 °C
1.2: 0 °C
2.1: sodium tetrahydroborate / ethanol / 0.5 h / 0 °C

References:

Briard, Emmanuelle;Rudolph, Bettina;Desrayaud, Sandrine;Krauser, Joel A.;Auberson, Yves P. [ChemMedChem,2015,vol. 10,# 6,p. 1008 - 1018]

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3-Ethyl-4-(hydroxyMethyl)benzonitrile

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