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ChemicalBook CAS DataBase List 3-FLUORO-3-PHENYLAZETIDINE HCL
1126650-56-3

3-FLUORO-3-PHENYLAZETIDINE HCL synthesis

3synthesis methods
1-Azetidinecarboxylic acid, 3-fluoro-3-phenyl-, 1,1-dimethylethyl ester

1126650-55-2
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3-FLUORO-3-PHENYLAZETIDINE HCL

1126650-56-3
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Yield:1126650-56-3 68%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane;water at 20; for 1 h;

References:

Van Hende, Eva;Verniest, Guido;Deroose, Frederik;Thuring, Jan-Willem;Macdonald, Gregor;De Kimpe, Norbert [Journal of Organic Chemistry,2009,vol. 74,# 5,p. 2250 - 2253] Location in patent:supporting information; experimental part