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3-fluoro-4-iodopyridin-2-amine synthesis

2synthesis methods
851386-34-0 Synthesis
2,3-Difluoro-4-iodopyridine

851386-34-0
122 suppliers
$16.00/100mg

3-fluoro-4-iodopyridin-2-amine

1269440-67-6
27 suppliers
inquiry

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Yield:1269440-67-6 85%

Reaction Conditions:

with 1-Imino-ethanamine hydrochloride;sodium hydroxide in lithium hydroxide monohydrate;dimethyl sulfoxide at 130; for 24 h;Schlenk technique;chemoselective reaction;

References:

Li, Yibiao;Huang, Shuo;Liao, Chunshu;Shao, Yan;Chen, Lu [Organic and Biomolecular Chemistry,2018,vol. 16,# 41,p. 7564 - 7567] Location in patent:supporting information