3-Fluorophenetole synthesis
- Product Name:3-Fluorophenetole
- CAS Number:458-03-7
- Molecular formula:C8H9FO
- Molecular Weight:140.15
372-20-3
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584-08-7
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75-03-6
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458-03-7
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$6.00/1g
Yield:-
Reaction Conditions:
in acetone
Steps:
1 N-(2-(2-Ethoxy-6-fluoro)phenethyl)-N'-(2-thiaozolyl)thiourea
1) 3-Fluorophenol (20.0 g, 178.4 mmol), ethyl iodide (83.5 g, 535.2 mmol) and K2 CO3 (49.3 g, 356.8 mmol) in 250 ml of acetone were stirred at 50° C. overnight. The mixture was filtered and evaporated to give 1-ethoxy-3-fluorobenzene. Yield 19.84 g (79%). 1 H-NMR (250 MHz, CDCl3): δ7.20 (q, 1H, phenyl), 6.69-6.57 (m, 3H, phenyl), 4.00 (q, 2H, CH2 CH3), 1.40 (t, 3H, CH2 CH3).
References:
Medivir AB US5593993, 1997, A
64-17-5
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1996-38-9
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462-06-6
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458-03-7
87 suppliers
$6.00/1g