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ChemicalBook CAS DataBase List 3-FORMYL-1H-INDOLE-6-CARBONITRILE

3-FORMYL-1H-INDOLE-6-CARBONITRILE synthesis

3synthesis methods
-

Yield:83783-33-9 60%

Reaction Conditions:

with tert.-butylhydroperoxide;ruthenium(III)chloride hydrate;trimethylpyruvic acid in N-methyl-acetamide at 25; for 24 h;Inert atmosphere;regioselective reaction;

References:

Wu, Wenliang;Su, Weiping [Journal of the American Chemical Society,2011,vol. 133,# 31,p. 11924 - 11927] Location in patent:supporting information; experimental part