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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

3-Hydroxy-1-azabicyclo[2.2.2]octane-3-Methanol synthesis

1synthesis methods
Spiro[oxirane-2,3'-quinuclidine]

41353-91-7
47 suppliers
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3-Hydroxy-1-azabicyclo[2.2.2]octane-3-Methanol

61573-79-3
18 suppliers
$195.00/100mg

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Yield:61573-79-3 48%

Reaction Conditions:

with perchloric acid at 20; for 18 h;Ring cleavage;

References:

Mullen;Napier;Balestra;Decory;Hale;Macor;Mack;Loch III;Wu;Kover;Verhoest;Sampognaro;Phillips;Zhu;Murray;Griffith;Blosser;Gurley;Machulskis;Zongrone;Rosen;Gordon [Journal of Medicinal Chemistry,2000,vol. 43,# 22,p. 4045 - 4050]