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59269-93-1

3-HYDROXY-2,2-DIMETHYLINDAN-1-ONE synthesis

5synthesis methods
-

Yield:59269-93-1 74%

Reaction Conditions:

with sodium tetrahydroborate in ethanol at -30; for 1 h;

References:

Papillon, Julien P. N.;Adams, Christopher M.;Hu, Qi-Ying;Lou, Changgang;Singh, Alok K.;Zhang, Chun;Carvalho, Jose;Rajan, Srinivan;Amaral, Adam;Beil, Michael E.;Fu, Fumin;Gangl, Eric;Hu, Chii-Whei;Jeng, Arco Y.;LaSala, Daniel;Liang, Guiqing;Logman, Michael;Maniara, Wieslawa M.;Rigel, Dean F.;Smith, Sherri A.;Ksander, Gary M. [Journal of Medicinal Chemistry,2015,vol. 58,# 11,p. 4749 - 4770]