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39850-43-6

3-hydroxy-3-phenylpropanal synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 77 percent / chiral borane complex / CH2Cl2 / 3 h / -78 °C
2: 80percent AcOH / H2O / 0.17 h / Ambient temperature

References:

Kiyooka, Syun-ichi;Kaneko, Yuichi;Komura, Misako;Matsuo, Hidehito;Nakano, Masahito [Journal of Organic Chemistry,1991,vol. 56,# 7,p. 2276 - 2278]