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ChemicalBook CAS DataBase List 3-Hydroxy-cyclopentanecarboxylic acid benzyl ester

3-Hydroxy-cyclopentanecarboxylic acid benzyl ester synthesis

4synthesis methods
benzyl cyclopent-3-enecarboxylate

130762-09-3
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3-Hydroxy-cyclopentanecarboxylic acid benzyl ester

916736-76-0
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Yield:916736-76-0 79%

Reaction Conditions:

Stage #1: benzyl cyclopent‐3‐ene‐1‐carboxylatewith Wilkinson's catalyst;benzo[1,3,2]dioxaborole
Stage #2: with hydrogen in tetrahydrofuran;

References:

Gardner, Daniel S.;Santella III, Joseph B.;Duncia, John V.;Carter, Percy H.;Dhar, T.G.Murali;Wu, Hong;Guo, Weiwei;Cavallaro, Cullen;Van Kirk, Katy;Yarde, Melissa;Briceno, Stephanie W.;Robert Grafstrom;Liu, Richard;Patel, Sima R.;Tebben, Andrew J.;Camac, Dan;Khan, Javed;Watson, Andrew;Yang, Guchen;Rose, Anne;Foster, William R.;Cvijic, Mary Ellen;Davies, Paul;Hynes Jr., John [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 13,p. 3833 - 3840]