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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List 3-Hydroxybicyclo[1.1.1]pentane-1-carboxylic acid

3-Hydroxybicyclo[1.1.1]pentane-1-carboxylic acid synthesis

1synthesis methods
Bicyclo[1.1.1]pentan-1-ol, 3-phenyl-, 1-acetate

83249-06-3
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3-Hydroxybicyclo[1.1.1]pentane-1-carboxylic acid

83249-08-5
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83249-07-4 Synthesis
3-(acetyloxy)bicyclo[1.1.1]pentane-1-carboxylic acid

83249-07-4
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Yield: 52%

Reaction Conditions:

with ruthenium(IV) oxide;sodium hypochlorite in tetrachloromethane for 48 h;

References:

Applequist, Douglas E.;Renken, Terry L.;Wheeler, James W. [Journal of Organic Chemistry,1982,vol. 47,# 25,p. 4985 - 4995]