ChemicalBook CAS DataBase List 3-hydroxynaphthalene-2-carbaldehyde

3-hydroxynaphthalene-2-carbaldehyde synthesis

7synthesis methods

Product Name:3-hydroxynaphthalene-2-carbaldehyde
CAS Number:581-71-5
Molecular formula:C11H8O2
Molecular Weight:172.18

56679-88-0 Synthesis

56679-88-0
52 suppliers
$22.00/250mg

581-71-5
50 suppliers
$60.00/25mg

Yield: 99%

Reaction Conditions:

with aluminum (III) chloride in dichloromethane at 20; for 8 h;

Steps:

8
The compound was dissolved VII-1 (2mmol, 1equiv) 20mL of dichloromethane,An excess of AlCl3,In dry oxygen-free state holding 8h,The reaction was quenched with water and extracted with dichloromethane,After drying spin dry,A silica gel column (PE: EA = 8: 1),To give Compound VIII-1 (99%);

References:

East China University of Science and Technology;Wang, Limin;Wu, Xunshen;Yang, Yang;Wu, Shengying;Wang, Feng;Wang, Guifeng;Tian, He;Wang, Zhenyan;Chen, Lirong;Huang, Zhuo CN105601608, 2016, A Location in patent:Paragraph 0092; 0095