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3-isopropoxybenzonitrile synthesis

2synthesis methods
-

Yield:363185-45-9 78%

Steps:

R.46 3-(1-Methylethoxy)benzonitrile

REFERENCE EXAMPLE 46 3-(1-Methylethoxy)benzonitrile The title compound was objected from 2-propanol and 3-fluorobenzonitrile by the method similar to that in Reference Example 38. Yield: 78%. 1H NMR (CDCl3) δ 1.35 (6H, d, J = 6.0 Hz), 4.51-4.63 (1H, m), 7.07-7.13 (2H, m), 7.21 (1H, dt, J = 7.6, 1.2 Hz), 7.36 (1H, td, J = 7.6, 1.4 Hz).

References:

EP1270577,2003,A1