3'-METHOXY-3-PHENYLPROPIOPHENONE synthesis

9synthesis methods

Product Name:3'-METHOXY-3-PHENYLPROPIOPHENONE
CAS Number:76106-76-8
Molecular formula:C16H16O2
Molecular Weight:240.3

100-51-6 Synthesis

100-51-6
1380 suppliers
$5.00/100g

586-37-8 Synthesis

586-37-8
313 suppliers
$10.00/5g

76106-76-8
8 suppliers
$437.00/1g

Yield:76106-76-8 91%

Reaction Conditions:

with C₃₈H₃₆Cl₄Ir₂N₄;caesium carbonate in tert-Amyl alcohol; for 12 h;Reflux;

Steps:

17 Example 17: 1-(3-methoxyphenyl)-3-phenylpropan-1-one

A mixture of 3-methoxyacetophenone (75 mg, 0.5 mmol),Cat. [Ir] (5.4 mg, 0.005 mmol, 1.0 mol%),Cesium carbonate (33 mg, 0.1 mmol, 0.2 equiv.),Benzyl alcohol (65 mg, 0.6 mmol)And tert-amyl alcohol (1 ml) were successively added to a 5 mL round bottom flask.The reaction mixture was refluxed in air for 12 hours,Cool to room temperature.Rotate the solvent to remove the solvent,The purified title compound was then purified by column chromatography (developing solvent: petroleum ether / ethyl acetate)Yield: 91%

References:

CN106478395,2017,A Location in patent:Paragraph 0105; 0106; 0107; 0108; 0109

100-42-5 Synthesis