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(3-METHOXY-PHENYL)-THIOPHEN-2-YL-METHANOL synthesis

1synthesis methods
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Yield:327070-53-1 69%

Reaction Conditions:

Stage #1: 3-methoxyphenyl bromidewith magnesium in tetrahydrofuran at 20; for 0.5 h;
Stage #2: thiophene-2-carbaldehyde in tetrahydrofuran at 20; for 1.5 h;Further stages.;

References:

Parai, Maloy Kumar;Panda, Gautam;Chaturvedi, Vinita;Manju;Sinha, Sudhir [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 1,p. 289 - 292]