3-Methyl-benzo[b]thiophene-2-boronic acid synthesis
1synthesis methods
- Product Name:3-Methyl-benzo[b]thiophene-2-boronic acid
- CAS Number:912331-27-2
- Molecular formula:C9H9BO2S
- Molecular Weight:192.04
![3-METHYLBENZO[B]THIOPHENE](/CAS/GIF/1455-18-1.gif)
Yield:912331-27-2 78%
Reaction Conditions:
Stage #1: 3-methylbenzo[b]thiophenewith n-butyllithium in tetrahydrofuran at -78; for 0.666667 h;
Stage #2: Triisopropyl borate in tetrahydrofuran at -78 - 20; for 3 h;
References:
Bai, Jian-Fei;Tang, Jianbo;Gao, Xiaolong;Jiang, Zhi-Jiang;Tang, Bencan;Chen, Jia;Gao, Zhanghua [Organic Letters,2022,vol. 24,# 25,p. 4507 - 4512] Location in patent:supporting information