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ChemicalBook CAS DataBase List 3-METHYL-PYRROLIDINE-3-CARBOXYLIC ACID

3-METHYL-PYRROLIDINE-3-CARBOXYLIC ACID synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium hydroxide / water / 16 h / 20 °C / pH 8 - 10
2: trifluoroacetic acid / dichloromethane / 17 h / 20 °C
3: hydrogen; palladium 10% on activated carbon / methanol / 1 h / 20 °C

References:

Nagata, Kazuhiro;Kuga, Yasushi;Higashi, Akinori;Kinoshita, Atsushi;Kanemitsu, Takuya;Miyazaki, Michiko;Itoh, Takashi [Journal of Organic Chemistry,2013,vol. 78,# 14,p. 7131 - 7136]

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