3-methylene-1-(phenylmethyl)pyrrolidine synthesis
- Product Name:3-methylene-1-(phenylmethyl)pyrrolidine
- CAS Number:150543-34-3
- Molecular formula:C12H15N
- Molecular Weight:173.25
775-16-6
321 suppliers
$31.80/1gm:
1779-49-3
589 suppliers
$5.00/10g
150543-34-3
11 suppliers
inquiry
Yield:150543-34-3 83%
Reaction Conditions:
Stage #1: Methyltriphenylphosphonium bromidewith potassium tert-butylate in tetrahydrofuran at 0; for 0.5 h;
Stage #2: N-benzyl-3-pyrrolidinone in tetrahydrofuran at 0 - 20; for 16.5 h;
References:
WO2006/122770,2006,A1 Location in patent:Page/Page column 79-80