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3-N-Cyclopentylpyridine-2,3-diamine synthesis

3synthesis methods
13534-99-1 Synthesis
3-Bromo-2-pyridinamine

13534-99-1
361 suppliers
$4.00/1g

1003-03-8 Synthesis
Cyclopentylamine

1003-03-8
212 suppliers
$10.00/1g

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Yield:1286273-74-2 82%

Reaction Conditions:

with chloro[2-(dicyclohexylphosphino)-3 ,6-dimethoxy-2’,4’, 6’-triisopropyl- 1,1’-biphenyl] [2-(2-aminoethyl)phenyl]palladium(II);lithium hexamethyldisilazane in tetrahydrofuran at 65; for 12 h;Inert atmosphere;

References:

Perez, Felix;Minatti, Ana [Organic Letters,2011,vol. 13,# 8,p. 1984 - 1987] Location in patent:supporting information; experimental part