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3-n-Hexyl-7-hydroxy-4-methylcoumarin synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 2 h / 0 - 60 °C
1.2: 0 - 100 °C
2.1: sulfuric acid / 6 h / 0 - 20 °C

References:

Arya, Anu;Kumar, Vinod;Mathur, Divya;Singh, Sukhdev;Brahma, Raju;Singh, Rajpal;Singh, Seema;Sharma;Parmar, Virinder S.;Prasad, Ashok K. [Journal of Heterocyclic Chemistry,2015,vol. 52,# 1,p. 1 - 14]