3-Nitro-2-pyridinethiol synthesis
- Product Name:3-Nitro-2-pyridinethiol
- CAS Number:38240-29-8
- Molecular formula:C5H4N2O2S
- Molecular Weight:156.16
5470-18-8
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$6.00/5g
38240-29-8
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$48.00/1g
Yield:-
Reaction Conditions:
with potassium hydroxide;thiourea in ethanol;water
Steps:
98.A 3-nitropyridine-2-thiol
Example 98A 3-nitropyridine-2-thiol 2-mercapto-3-nitropyridine was prepared by treating 3-nitro-2-chloro-pyridine (50 g, 0.0317 mol) with thiourea (24 g, 0.0317 mol) in 200 mL of ethanol at reflux for several hours. After the reaction mixture was allowed to cool, 7.19 mL solution of KOH (42.8 g in 115 mL of water) was added and the resulting mixture was heated at reflux for 3 hours. The crude reaction mixture was cooled to room temperature and then concentrated to 50% of its volume in vacuo.
References:
Pratt, John K.;Betebenner, David A.;Donner, Pamela L.;Green, Brian E.;Kempf, Dale J.;McDaniel, Keith F.;Maring, Clarence J.;Stoll, Vincent S.;Zhang, Rong US2004/162285, 2004, A1
76880-29-0
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$39.20/1g
38240-29-8
79 suppliers
$48.00/1g
20887-95-0
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$27.00/250mg