![](/CAS/GIF/3586-15-0.gif)
3-PHENOXYBENZOYL CHLORIDE synthesis
- Product Name:3-PHENOXYBENZOYL CHLORIDE
- CAS Number:3586-15-0
- Molecular formula:C13H9ClO2
- Molecular Weight:232.66
![Oxalyl chloride](/CAS/GIF/79-37-8.gif)
79-37-8
464 suppliers
$17.67/10gm:
![3-Phenoxybenzoic acid](/CAS/GIF/3739-38-6.gif)
3739-38-6
195 suppliers
$6.00/1g
![3-PHENOXYBENZOYL CHLORIDE](/CAS/GIF/3586-15-0.gif)
3586-15-0
33 suppliers
$45.95/250mgs:
Yield:3586-15-0 1.12 g (53%)
Reaction Conditions:
in diethyl ether;dichloromethane;
Steps:
6.a (a)
(a) 3-Phenoxybenzoyl Chloride: This compound was prepared as generally described in (Patent Publication No. GB 1052390). To 3-phenoxybenzoic acid (1.95 g, 9.10 mmol) dissolved in CH2Cl2 (45 mL) was added oxalyl chloride (0.89 mL, 10.01 mmol) followed by a drop of DMF. The reaction mixture was stirred overnight at rt and the solvent was removed in vacuo. The residue was taken up in Et2O, and the liquid was carefully decanted away from any remaining solid. The Et2O was evaporated and the resulting crude product was purified by short path vacuum distillation (bp=139° C./3 mm Hg) to give 1.12 g (53%) of a clear liquid: IR (neat) 1755, 1584 cm-1; 1H NMR (CDCl3) δ 7.02-7.05 (m, 2H), 7.16-7.21 (m, 1H), 7.29-7.33 (m, 1H), 7.37-7.49 (m, 3H), 7.70-7.71 (m, 1H), 7.84-7.87 (m, 1H).
References:
US6548494,2003,B1
![3-Phenoxybenzoic acid](/CAS/GIF/3739-38-6.gif)
3739-38-6
195 suppliers
$6.00/1g
![3-PHENOXYBENZOYL CHLORIDE](/CAS/GIF/3586-15-0.gif)
3586-15-0
33 suppliers
$45.95/250mgs:
![Bromobenzene](/CAS/GIF/108-86-1.gif)
108-86-1
496 suppliers
$10.00/5g
![3-PHENOXYBENZOYL CHLORIDE](/CAS/GIF/3586-15-0.gif)
3586-15-0
33 suppliers
$45.95/250mgs:
![m-Cresol](/CAS/GIF/108-39-4.gif)
108-39-4
466 suppliers
$13.00/25g
![3-PHENOXYBENZOYL CHLORIDE](/CAS/GIF/3586-15-0.gif)
3586-15-0
33 suppliers
$45.95/250mgs:
![Chlorobenzene](/CAS/GIF/108-90-7.gif)
108-90-7
644 suppliers
$10.00/25G
![3-PHENOXYBENZOYL CHLORIDE](/CAS/GIF/3586-15-0.gif)
3586-15-0
33 suppliers
$45.95/250mgs: