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3-PHENYL-2-PROPYN-1-AMINE synthesis

11synthesis methods
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Yield:78168-74-8 96 %

Reaction Conditions:

Stage #1: (3-phenyl-prop-2-ynyl)-carbamic acid tert-butyl esterwith hydrogenchloride in tetrahydrofuran;1,4-dioxane at 20;
Stage #2: with water;sodium hydroxide in tetrahydrofuran;

References:

Ji, Pengwei;Liu, Xiaopei;Xu, Jiwei;Zhang, Xu;Guo, Jianhua;Chen, Wen-Wen;Zhao, Baoguo [Angewandte Chemie - International Edition,2022,vol. 61,# 48,art. no. E202206111][Angew. Chem.,2022,vol. 134,# 48] Location in patent:supporting information

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